Diagnostics / Literature

Diagnostics Literature

Here you can search a selected list of NGAL literature relevant for diagnostic purposes.

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Bangert K (2013) ASN Kidney Week

Analysis of plasma and urine NGAL monomer and homodimer in 151 Severe sepsis patients.

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Source
http://ngal.com/media/65680/bangert_k_2013_asn_-_fr-po017.pdf
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Di Nardo M (2013) Blood Purif 35(1-3):172-6

We hypothesized that sepsis could have an impact on the sensitivity of serum and urinary neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (CysC) for acute kidney injury (AKI) diagnosis in critically ill children.

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Source
http://www.ncbi.nlm.nih.gov/pubmed/23428967
Date

Heyne N (2012) Transplantation

Urinary neutrophil gelatinase-associated lipocalin (NGAL) has emerged an early marker protein, predicative of acute kidney injury (AKI) in various clinical settings. 

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Source
http://www.ncbi.nlm.nih.gov/pubmed/22513480
Date

Huber W (2012) J CLI 36:10-12

Sepsis frequently results in acute kidney injury (AKI). Although AKI markedly contributes to mortality in sepsis, its diagnosis is frequently delayed due to limitations of current biomarkers of renal impairment. Neutrophil-gelatinase-associated lipocalin (NGAL) has been demonstrated to be a biomarker of early AKI.

To download as pdf please click here 

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Source
http://www.cli-online.com/featured-articles/early-detection-of-acute-kidney-injury-in-sepsis-how-about-ngal/index.html
Date

Jeong TD (2012) Clin Transplant

An evaluation of the utility of urine and plasma neutrophil gelatinase-associated lipocalin (NGAL) concentrations as biomarkers of AKI during and after liver transplantation.

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Source
http://www.ncbi.nlm.nih.gov/pubmed/22404749
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Bataille A (2011) Tranplant 15;92(9):1024-30

This prospective observational study aimed to assess the relevance of serial postoperative plasma neutrophil gelatinase-associated lipocalin (NGAL) measurements on prediction of early renal transplant function.

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Source
http://www.ncbi.nlm.nih.gov/pubmed/21956199
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Ostermann M (2011) J CLI 35:10-12

Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as a promising biomarker for acute kidney injury (AKI). The ultimate goal is for NGAL to enable clinicians to intervene as early as possible and to change the prognosis of AKI.

To download as pdf please click here

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Source
http://www.cli-online.com/index.php?id=3198
Date

Ricci Z (2011) Crit Care 29;15:R160

A study of Fenoldopam efficacy as a pretreatment to avoid AKI on cardiopulmonary bypass pediatric patients using NGAL for definition of AKI...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/21714857
Date

Haase M (2011) J Am Coll Cardiol 26;57:1752-61

The aim of this study was to test the hypothesis that, without diagnostic changes in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels identify patients with subclinical acute kidney injury (AKI) and therefore worse prognosis...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/21511111
Date

de Geus HR (2011) Am J Respir Crit Care Med 183:907-914

Measured at intensive care unit admission (ICU), the predictive value of neutrophil gelatinase-associated lipocalin (NGAL) for severe acute kidney injury (AKI) is unclear...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/20935115
Date

Du Y (2011) Pediatr Nephrol 26:267-74

We conducted a prospective study in pediatric patients presenting to an emergency center (EC) to (1) test the ability of urinary acute kidney injury (AKI) biomarkers to predict AKI presence and severity...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/20978799
Date

Heise D (2011) Eur J Cardiothorac Surg 39:38-43

Acute renal injury is a frequent complication after cardiac surgery that necessitates additional treatment and increases mortality...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/20650648
Date

Hollmen ME (2011) Kidney Int 79:89-98

Delayed graft function (DGF), especially long-lasting DGF, complicates kidney transplant outcome. Neutrophil gelatinase-associated lipocalin (NGAL) is an acute kidney injury marker...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/20861824
Date

Portal AJ (2010) Liver Transpl 16:1257-66

Postoperative acute kidney injury (AKI) increases morbidity and mortality after liver transplantation (LT). Novel methods of assessing AKI including cystatin C (CyC) and neutrophil gelatinase-associated lipocalin (NGAL)...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/21031541
Date

Devarajan D (2010) Nephrol (Carlton) 15:419-28

Acute kidney injury (AKI) is a common and serious condition, the diagnosis of which currently depends on functional markers such as serum creatinine measurements. Unfortunately, creatinine is a delayed and unreliable indicator of AKI...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/20609093
Date

Moore E (2010) Minerva Anestesiol 76:425-40

Acute kidney injury (AKI) is common after major surgery and reportedly occurs in approximately 36% of ICU patients (RIFLE Risk/Injury/ Failure categories)...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/20473256
Date

Prabhu A (2010) Ann Vasc Surg 24:525-31

Acute kidney injury (AKI) is a significant cause of morbidity and mortality following cardiac surgery throughout the world...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/20363104
Date

Cruz DN (2010) Int Care Med 36:444-51

Neutrophil gelatinase-associated lipocalin (NGAL) is a useful marker for acute kidney injury (AKI), particularly when the timing of renal insult is known...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/19956925
Date

Kümpers P (2010) Crit Care 14:R9

Neutrophil gelatinase-associated lipocalin (NGAL) is a promising novel biomarker that correlates with the severity and outcome of acute kidney injury (AKI)...

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Source
http://www.ncbi.nlm.nih.gov/pubmed?term=K%C3%BCmpers%20ngal
Date

Hall IE (2010) J Am Soc Nephrol 21:189-97

Current methods for predicting graft recovery after kidney transplantation are not reliable. We performed a prospective, multicenter, observational cohort study of deceased-donor kidney transplant patients...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/19762491
Date

Tuladhar SM (2009) Cardiovasc Pharmacol 53:261-6

Cardiopulmonary bypass (CPB) is associated with a significant risk of postoperative renal dysfunction...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/19247188
Date

Malyszko J (2009) Transplant Proc 41:158-61

Few biomarkers exist to monitor chronic kidney disease (CKD). Neutrophil gelatinase-associated lipocalin (NGAL), a member of lipocalin family...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/19249502
Date

Bolignano D (2008) Am J Kidney Dis 52:595-605

Neutrophil gelatinase-associated lipocalin (NGAL) is a protein belonging to the lipocalin superfamily initially found in activated neutrophils, in accordance with its role as an innate antibacterial factor...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18725016
Date

Nickolas TL (2008) Ann Intern Med 3;148:810-9

To test the sensitivity and specificity of a single measurement of urinary neutrophil gelatinase-associated lipocalin (NGAL) and other urinary proteins to detect acute kidney injury...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18519927
Date

Bennett M (2008) Clin J Am Soc Nephrol 3:665-73

The authors have previously shown that urine neutrophil gelatinase-associated lipocalin (NGAL), measured by a research ELISA, is an early predictive biomarker of acute kidney injury (AKI)...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18337554
Date

Wheeler DS (2008) Crit Care Med 36:1297-303

To validate serum neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for acute kidney injury in critically ill children with septic shock...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18379258
Date

Ling W (2008) Nephron Clin Pract 108:c176-81

Contrast-induced nephropathy (CIN) is at present the third leading cause of hospital-acquired acute kidney injury (AKI). Traditionally, it is diagnosed by measuring the increase of the serum creatinine...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18287807
Date

Wagener G (2008) Am J Nephrol 28:576-82

Use of aprotinin has been associated with acute kidney injury after cardiac surgery. Neutrophil gelatinase-associated lipocalin (NGAL) is a novel, very sensitive marker for renal injury...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18264006
Date

Kusaka M (2008) Cell Transplant 17:129-34

Because of a worldwide shortage of renal grafts, kidneys procured from donors after cardiac death (DCD) have recently become an important source of renal transplants...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18472448
Date

Xin C (2008) Ren Fail 30:904-13

About 30-50% patients develop acute kidney injury (AKI) after cardiac surgery, which is still diagnosed by serum creatinine on clinic...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18925531
Date

Dent CL (2007) Crit Care 11:R127

Acute kidney injury (AKI) is a frequent complication of cardiopulmonary bypass (CPB). The lack of early biomarkers has impaired our ability to intervene in a timely manner...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/18070344
Date

Hirsch R (2007) Pediatr Nephrol 22:2089-95

We hypothesized that neutrophil gelatinase-associated lipocalin (NGAL) is an early predictive biomarker of contrast-induced nephropathy (CIN)...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/17874137
Date

Mori K (2007) Kidney Int 71:967-70

Neutrophil gelatinase-associated lipocalin (Ngal, 24p3, SIP24, lipocalin 2, or siderocalin) was originally purified from neutrophils, but with unknown function...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/17342180
Date

Bachorzewska-Gajewska H (2006) Am J Nephrol 26:287-92

The value of neutrophil-gelatinase-associated lipocalin (NGAL), a novel biomarker in the detection of acute renal failure in children after cardiac surgery...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/16772710
Date

Chertow GM (2005) J Am Soc Nephrol 16:3365-3370

The marginal effects of acute kidney injury on in-hospital mortality, length of stay (LOS), and costs have not been well described...

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Source
http://www.ncbi.nlm.nih.gov/pubmed/16177006
Date